Effect of dietary lipids on rat alveolar macrophage function

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Title: Effect of dietary lipids on rat alveolar macrophage function
Author: Mehta, Sangeeta R.
Abstract: An in vitro assay has been developed to measure bacterial uptake by rat alveolar macrophages. The assay is used to study the effect of a diet rich in high omega-6 linoleic acid on the phagocytic response of the macrophages obtained from young and old rats. Within the range of diets studied, no significant difference (p<0.05) is observed in the phagocytic capability of macrophages from young rats. Significant difference is observed between diet groups for the old rats (p<0.05), with the group on a fat-rich diet showing suppressed phagocytic response. Significant difference is also found between age groups for the same diet (p<0.05), older animals showing suppressed response.
Record URI: http://hdl.handle.net/1850/11225
Date: 1991-06

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