Decide vaccine prices and subsidies for developing countries

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dc.contributor.advisor Proaño, Rubén
dc.contributor.author Zhang, Wenbo
dc.date.accessioned 2012-02-06T15:35:33Z
dc.date.available 2012-02-06T15:35:33Z
dc.date.issued 2011-06-30
dc.identifier.uri http://hdl.handle.net/1850/14671
dc.description.abstract Vaccination has been deemed the most cost-effective way to fight against preventable diseases and improve global health. In recent years, expensive combination vaccines which provide multiple antigens in a single shot have been developed to replace traditional monovalent vaccines and have become the preferred choice of healthcare systems in industrialized countries. High prices have not only barricaded low-income countries from accessing combination vaccines but also lure vaccine manufacturers to shift their production capacity from making traditional vaccines to combination vaccines. Such a shift could eventually lead to shortages on the vaccine supply for low-income countries. This work extends the ABP model proposed by Proaño which optimally prices vaccines under tiered pricing strategy to make them affordable and available across different market segments. This thesis first introduces a heuristic method to solve the ABP. Second, this thesis presents an optimization model to decide the minimum amount of subsidy needed to make an expensive combination vaccine affordable to people in a low-income country. en_US
dc.language.iso en_US en_US
dc.subject Heuristics en_US
dc.subject Optimization en_US
dc.subject Pricing en_US
dc.subject Social surplus en_US
dc.subject Subsidy en_US
dc.subject Vaccine en_US
dc.subject.lcc RM281 .Z43 2011
dc.subject.lcsh Vaccines--Prices--Developing countries en_US
dc.subject.lcsh Subsidies--Developing countries en_US
dc.subject.lcsh Epidemics--Prevention en_US
dc.title Decide vaccine prices and subsidies for developing countries en_US
dc.type Thesis en_US
dc.description.college Kate Gleason College of Engineering en_US
dc.description.department Department of Industrial & Systems Engineering en_US

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