Visualizing actin regulatory proteins & the mechanoelectrical Ion channel in inner ear stereocilia

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Title: Visualizing actin regulatory proteins & the mechanoelectrical Ion channel in inner ear stereocilia
Author: Tu, Chih-Tao
Abstract: My thesis was a continuation of the "3D Virtual Ear Animation" project for the Imagine RIT Festival held in spring 2010. I worked with Dr. David Corey, a Howard Hughes Medical Institute (HHMI) Investigator, whose research publications I had been reading since the spring of 2010. I learned about information that explains how hearing is transformed into neural signals ultimately perceived by the brain. Motivated by the presence of hearing-impaired students on the campus, I decided to continue this animation project. Another motivation for this topic was the lack of illustrations and animations that captured the latest discoveries, particularly the essential protein molecules that are involved. I had taken advantage of the discoveries made in Dr. Corey's laboratory. I expect it will be useful for teaching and educating the public on websites devoted to hearing loss. The goal was to illustrate the new molecular understanding of how hearing works. This will help the Deaf become more aware of the causes of hearing loss, and may encourage researchers to invent new solutions to hearing loss that are better than hearing aids.
Record URI: http://hdl.handle.net/1850/15122
Date: 2/22/2012

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