Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1

Show full item record

Title: Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1
Author: Smiley, Stephen; Reers, Martin; Mottola-Hartshom, Cristina; Lin, Mei; Chen, Ann; Smith, Thomas; Steele, Glenn Jr.; Chen, Lan Bo
Abstract: By using a potential-dependent J-aggregate-forming delocalized lipophilic cation, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide (JC-1), we find that membrane potentials across mitochondria in a living cell can be heterogeneous. Remarkably, even within a long contiguous mitochondrion, regional heterogeneity in membrane potentials appears to be possible.
Description: Article may be found at: http://www.pnas.org/cgi/reprint/88/9/3671
Record URI: http://hdl.handle.net/1850/2342
Date: 1991-05-01

Files in this item

Files Size Format View
NASArchivePolicy.pdf 39.11Kb PDF View/Open

The following license files are associated with this item:

This item appears in the following Collection(s)

Show full item record

Search RIT DML


Advanced Search

Browse