ALFRED: an allele frequency database for diverse populations and DNA polymorphisms

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Title: ALFRED: an allele frequency database for diverse populations and DNA polymorphisms
Author: Cheung, Kei-Hoi; Osier, Michael; Kidd, Judith; Pakstis, Andrew; Miller, Perry; Kidd, Kenneth
Abstract: We have developed a publicly accessible database (ALFRED, the ALlele FREquency Database) that catalogues allele frequency data for a wide range of population samples and DNA polymorphisms. This database is web-accessible through our laboratory (Kidd Lab) Web site: http://info.med.yale.edu/genetics/kkidd . ALFRED currently contains data on 60 populations and 156 genetic systems including single nucleotide polymorphisms (SNPs), short tandem repeat polymorphisms (STRPs), variable number of tandem repeats (VNTRs) and insertion–deletion polymorphisms. While data are not available for all population–DNA polymorphism combinations, over 2000 allele frequency tables have been entered. Our database is designed (i) to address our specific research requirements as well as broader scientific objectives; (ii) to allow researchers and interested educators to easily navigate and retrieve data of interest to them; and (iii) to integrate links to other related public databases such as dbSNP, GenBank and PubMed.
Description: Article may be found at: http://nar.oxfordjournals.org/cgi/content/full/28/1/361
Record URI: http://hdl.handle.net/1850/2421
Date: 2000-01-01

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