Inhibition and inactivation of liver aldolase

Show full item record

Title: Inhibition and inactivation of liver aldolase
Author: Waud, John; Feldman, Ellen; Schray, Keith
Abstract: Substrate analogs xylulose 1,5-bisphosphate, glucitol 1,6-bisphosphate, alpha-2,5-anhydroglucitol 1,6-bisphosphate, alpha-, beta-methyl fructofuranoside 1,6-bisphosphate, ribulose 1,5-bisphosphate, ribulose 5-phosphate, and ribose 5-phosphate and inactivating agents 1-chloro-2, 4-dinitrobenzene, 4-hydroxymercuribenzoate, and pyridoxal phosphate were examined for their effects on liver aldolase. These studies support the use of the beta-anomer and acyclic form as substrate. They also suggest that the liver enzyme active site is similar to the muscle enzyme but with a much weaker 6-phosphate binding site.
Record URI:
Publishers URL:
Date: 1981-02

Files in this item

Files Size Format View

An open access version of this file is not available. Check "Publisher URL" field for access

This item appears in the following Collection(s)

Show full item record

Search RIT DML

Advanced Search