Micro-molded cannulae for intracochlear infusions in small rodents

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dc.contributor.author Johnson, Dean en_US
dc.contributor.author Zhu, X. en_US
dc.contributor.author Frisina, Robert D. en_US
dc.contributor.author Borkholder, David en_US
dc.date.accessioned 2008-01-25T21:24:32Z en_US
dc.date.available 2008-01-25T21:24:32Z en_US
dc.date.issued 2007-08-23 en_US
dc.identifier.uri http://hdl.handle.net/1850/5542 en_US
dc.description This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder. en_US
dc.description.abstract The design, fabrication, and testing of microcannulae with integrated insertion stops is presented. The micro-cannulae were engineered through the use of a silicon micro-mold fabricated via bulk-silicon micro-machining techniques. The use of microelectronic fabrication techniques allows precise control of three critical parameters, insertion depth, interface contact area, and tubing out of round. Worst case variations were found to be 5μm for insertion depth, 502μm2 for interface contact area, and 7% for tip out of round. Histological evaluation revealed the cannula to be located correctly within the basal portion of scala tympani. en_US
dc.publisher The 29th Annual International IEEE Engineering in Medicine and Biology Society Conference en_US
dc.subject Drug delivery device en_US
dc.subject Microfabrication en_US
dc.subject Micromolding en_US
dc.subject Implantable device en_US
dc.subject Cannulae en_US
dc.subject Mouse en_US
dc.title Micro-molded cannulae for intracochlear infusions in small rodents en_US
dc.type Proceedings en_US

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