Intermodality nonrigid breast-image registration

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dc.contributor.author Coman, Ioana
dc.contributor.author Krol, Andrzej
dc.contributor.author Feiglin, David
dc.contributor.author Lipson, Edward
dc.contributor.author Mandel, James
dc.contributor.author Baum, Karl
dc.contributor.author Unlu, Mehmet
dc.contributor.author Li, Wei
dc.date.accessioned 2008-09-21T01:56:37Z
dc.date.available 2008-09-21T01:56:37Z
dc.date.issued 2004
dc.identifier.isbn 0-7803-8388-5
dc.identifier.uri http://hdl.handle.net/1850/7058
dc.description IEEE international symposium on biomedical imaging. en_US
dc.description.abstract We investigated nonrigid co-registration of PET and MR breast images to improve diagnostic specificity in difficult-to-interpret mammograms, and ultimately to avoid biopsy. A deformable breast model based on a finite-element method (FEM) was employed. The FEM “loads” were taken as the observed intermodal displacements of several fiducial skin markers placed on the breast and visible in PET and MRI. The analogy between orthogonal components of the displacement field and the temperature differences in a steady-state heat transfer (SSHT) in solids was adopted. The model allows estimation of the intermodal breast deformation for every location within the breast. To test our model, an elastic breast phantom with simulated internal "lesions" and external markers was imaged with PET and MRI. We estimated fiducial- and target-registration errors vs. number and location of the fiducials. We established that SSHT approach using external fiducial markers is accurate to within ~5 mm. en_US
dc.language.iso en_US en_US
dc.publisher IEEE en_US
dc.title Intermodality nonrigid breast-image registration en_US
dc.type Article en_US

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